Associate Director, Portfolio Operations

Voyager Therapeutics

Voyager Therapeutics

Lexington, MA, USA
Posted on Friday, March 29, 2024

About Voyager Therapeutics

Voyager Therapeutics, Inc. (Nasdaq: VYGR) is a biotechnology company dedicated to leveraging the power of human genetics to modify the course of – and ultimately cure – neurological diseases. Our pipeline includes programs for Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), Parkinson’s disease, and multiple other diseases of the central nervous system. Many of our programs are derived from our TRACER™ AAV capsid discovery platform, which we have used to generate novel capsids and identify associated receptors to potentially enable high brain penetration with genetic medicines following intravenous dosing. Some of our programs are wholly owned, and some are advancing with partners including Alexion, AstraZeneca Rare Disease; Novartis Pharma AG; Neurocrine Biosciences, Inc.; and Sangamo Therapeutics, Inc. For more information, visit

Voyager Therapeutics® is a registered trademark, and TRACER™ is a trademark, of Voyager Therapeutics, Inc.

Job Summary

Voyager Therapeutics is seeking a highly skilled and experienced Associate Director of Portfolio Operations to join our portfolio management team. This individual will oversee all operational aspects of our portfolio, ensuring strategic alignment, resource management, and optimal performance. The successful candidate will play a key role in shaping Voyager's portfolio operations and driving growth in our pipeline of innovative therapies for severe neurological diseases.


  • Manage and oversee Voyager Therapeutics' portfolio operations, in alignment with the company's overall goals and objectives.
  • Generate regular reports/communications that summarize portfolio metrics, issues and documents/presentations for governance forums, senior management and Board of Directors
  • Manage R&D governance in a stage-appropriate manner to implement needed disciplines while preserving the agility and flexibility of a fast-growing biotech company.
  • Serve as R&D Lead and Partner with Finance to develop, manage, and track AOP and budget activities for Research and Development.
  • Liaise with Business Development on potential opportunities and program-specific competitive intelligence.
  • Partner with Program/Product Leader/PMs to shape program strategy and execution plan for assigned programs.
  • Build relationships with key stakeholders (team members and leadership) to ensure alignment of program plans with functional and corporate objectives.
  • Prepare program status update and presentations for appropriate governance bodies
  • Partner with the Finance team to develop and track portfolio budget.
  • Proactively identify and escalate gaps and challenges; managing team through scenario planning to solve problems.
  • Support development and scaling of stage-appropriate capabilities, tools, and processes as the company’s portfolio continues to grow.


  • Bachelor's degree in science, business, or related field required; MBA or advanced degree preferred. Preference for candidates with an education in both science and business.
  • Minimum of 10 years of progressive experience with minimum of 3+ years spent in program management, portfolio management, R&D Operations, or related field.
  • Must understand drug development stage gates, including preclinical, clinical phases, and regulatory milestones.
  • Strong understanding of financial markets, investment principles, portfolio optimization strategies, and risk management techniques.
  • Demonstrated leadership abilities, including experience fostering a collaborative and inclusive work environment.
  • Excellent analytical and quantitative skills, with the ability to interpret complex data, perform modeling, and make informed decisions.
  • Effective communication skills, both verbal and written, with the ability to articulate complex concepts clearly and concisely to diverse audiences, including senior management, stakeholders, and external partners.
  • Familiarity with regulatory requirements and compliance standards relevant to portfolio management, including SEC regulations and industry best practices.
  • Proven ability to thrive in a fast-paced, dynamic environment, with a high level of adaptability, flexibility, and resilience to changing priorities and business needs.
  • Strong attention to detail and a commitment to accuracy and precision in all aspects of work, including financial analysis, reporting, and documentation.
  • Ability to collaborate effectively with cross-functional teams, including research and development, finance, legal, and external partners, to achieve common goals and drive results.
  • Passion for Voyager Therapeutics' mission to develop transformative gene therapies for patients with severe neurological diseases, and a desire to make a meaningful impact in the field of biotechnology.