Vice President, Neuroscience (Neuroscience)

Voyager Therapeutics

Voyager Therapeutics

Cambridge, MA, USA
Posted on Tuesday, April 4, 2023

About Voyager

Voyager Therapeutics (Nasdaq: VYGR) is a biotechnology company dedicated to breaking through barriers in gene therapy and neurology. The potential of both disciplines has been constrained by delivery challenges; Voyager is leveraging innovative expertise in capsid discovery and deep neuropharmacology capabilities to address these constraints. Voyager’s TRACER AAV capsid discovery platform has generated novel capsids with high target delivery and blood-brain barrier penetration at low doses, potentially addressing the narrow therapeutic window associated with conventional gene therapy delivery vectors. This platform is fueling alliances with Pfizer Inc., Novartis and Neurocrine Biosciences as well as multiple programs in Voyager’s own pipeline. Voyager’s pipeline includes preclinical programs in Parkinson’s disease, Alzheimer’s disease, and amyotrophic lateral sclerosis (ALS), each with validated targets and biomarkers to enable a path to rapid potential proof-of-biology. For more information, visit www.voyagertherapeutics.com

Job Summary:

The Vice President, Neuroscience will provide leadership for advancing Voyager’s AAV gene therapy programs. We are seeking a highly motivated individual with demonstrated success in leading teams through early stage drug discovery to IND and experience in gene therapy applied toward CNS and musculoskeletal indications. This is an ideal position for an individual who is energetic and thrives in a team-oriented, fast-paced, and cross-disciplinary small biotech company environment. This role is located in Cambridge, MA.

Position Specific Responsibilities:

  • Leading, planning, and managing all aspects of the pre-clinical Neuroscience team responsible for exploratory and pipeline programs focused on CNS and neuromuscular disease.
  • Development and execution of program workplans, deliverables, and goals for Neuroscience to ensure goals are accomplished in a timely manner.
  • Team Leadership of group to develop and execute on pre-clinical program plans, including guidance and sharing of expertise across departments.
  • Cultivation of a culture for operational excellence and a data-driven, decision-oriented culture
  • Management of the Neuroscience budget and oversight of external CROs, academic, and business partners, including outreach and relationship building with KOLs
  • Attendance of relevant scientific conferences to network with academia and industry, and to stay current in relevant research.

Specialized Knowledge & Skills:

  • Highly motivated scientific leader with demonstrated success in early-stage drug discovery and experience in gene therapy applied toward CNS and musculoskeletal disease targets
  • In-depth familiarity with target validation and lead identification and optimization using molecular, cellular, and in vivo methodologies
  • Demonstrated knowledge and understanding of the preclinical drug development process
  • Ability to be highly productive in a fluid and fast-paced work environment
  • Experience moving programs to IND is strongly preferred
  • Outstanding team player who is able to work effectively across departments and is comfortable working on and prioritizing multiple projects in parallel
  • Strong publication record and experience in presenting research internally and externally
  • Ability to independently analyze and present data to scientific and senior leadership teams
  • Energetic and thrives in a team-oriented, fast-paced, and cross-disciplinary small biotech company environment.

Requirements:

Educational Requirements:

  • Ph.D in a relevant discipline, with a minimum of 10 years industry experience

Experience:

  • Minimum of 5 years’ experience in a supervisory role in industry
  • Significant experience with AAV gene therapy drug development, bench to bedside
  • Significant experience and demonstrated scientific leadership with drug discovery and development
  • Experience with biologics drug discovery and development
  • Experience within a small biotech environment
  • Experience in program/project leadership including project plan generation, timeline management and budget planning
  • Hands-on experience with in vivo disease model development and preclinical drug testing, with a demonstrated understanding of pharmacodynamics and pharmacokinetics