Manager, Inventory Planning

Vaxcyte

Vaxcyte

San Carlos, CA, USA
Posted on Wednesday, January 31, 2024
Company Profile:
Vaxcyte, Inc. (Nasdaq: PCVX) is a vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases. The Company is developing broad-spectrum conjugate and novel protein vaccines to prevent or treat bacterial infectious diseases. Vaxcyte’s lead candidate, VAX-24, is a 24-valent, broad-spectrum, carrier-sparing pneumococcal conjugate vaccine (PCV) being developed for the prevention of invasive pneumococcal disease (IPD). The Company is re-engineering the way highly complex immunizations are made through modern synthetic techniques, including advanced chemistry and our exclusively licensed XpressCFTM cell-free protein synthesis platform. Unlike conventional cell-based approaches, the Company’s system for producing difficult-to-make proteins and antigens is intended to accelerate its ability to efficiently create and deliver high-fidelity vaccines with enhanced immunological benefits. Vaxcyte’s pipeline also includes VAX-31, a 31-valent PCV candidate; VAX-A1, a prophylactic vaccine candidate designed to prevent Group A Strep infections; VAX-PG, a therapeutic vaccine candidate designed to slow or stop the progression of periodontal disease; and VAX-GI, a vaccine program designed to prevent Shigella. The Company is driven to eradicate or treat invasive bacterial infections, which have serious and costly health consequences when left unchecked. For more information, visit www.vaxcyte.com.
Vaxcyte, headquartered in San Carlos, CA, went public in June 2020 and currently has a team of approximately 180 employees and anticipates continued, significant growth. Following equity offerings in October 2022 and April 2023, which generated over $1.1 billion in net proceeds, the Company’s balance sheet is further strengthened to advance its pipeline of novel vaccines, including VAX-24. These financings followed positive data readouts from Vaxcyte’s Phase 1/2 proof-of-concept study evaluating VAX-24 in adults aged 18-64 and Phase 2 study in adults 65 and older. The Company believes these results support a best-in-class potential for VAX-24, which was designed to replace the current standard-of-care in adults and children. VAX-24 is being investigated for the prevention of IPD, which can be most serious for infants, young children, older adults and those with immune deficiencies or certain chronic health conditions. Given the global impact of pneumococcal disease remains significant, the public health community continues to advocate for vaccines that can offer broader protection to prevent IPD. Vaxcyte’s PCV franchise, consisting of VAX-24 and VAX-31, is designed specifically to address this need and has the potential to deliver the broadest protection for this very serious disease. We believe that our PCVs could receive regulatory approval based on successful completion of clinical studies utilizing well-defined surrogate immune endpoints, consistent with how other PCVs have obtained regulatory approval in the past, rather than requiring clinical field efficacy studies.
Summary:
This role is responsible for inventory planning and inventory management across our entire global network of suppliers and storage sites. This position plays a key role in ensuring Vaxcyte can execute its manufacturing plans on time, supply patients and deliver accurate and compliant financial reporting. This role will work closely with colleagues in Supply planning, Logistics, Quality, Process Development, Manufacturing Science and Technology (MSAT) and Finance.

Essential Functions:

  • Maintain up to date and accurate view of Vaxcyte inventory including Drug Product, Drug Substance, Intermediates and Raw Materials at each of our Suppliers, CMOs and storage sites.
  • Key information to be maintained includes batch, quantity, location, quality status, regulatory status, expiry date and version.
  • Provide Supply Planning and Quality groups a proactive view of batches that are approaching their expiry date. Confirm if shelf-life extension is possible and monitor progress to implement.
  • Monitor key performance indicators (KPIs) vs target for each material including production yield, concentration, consumption rate and waste.
  • Identify KPI performance trends and risks and work with Process Development, MSAT and Supply Planning to align on modified expectations as needed.
  • Monitor Vaxcyte production plans and identify the appropriate batches and containers to allocate to this production based on quality status, version, shelf life, regulatory status, sampling requirements and waste minimization.
  • Respond to material requests from Process Development and allocate inventory to their requests as appropriate.
  • Prepare shipping requests to transfer inventory to the locations where it is required.
  • Monitor our capacity utilization of subzero storage space and support capacity planning analysis.
  • Improve processes and tools for collecting and tracking inventory and production data.
  • Respond to questions from Finance regarding current inventory levels and transaction history.
  • Support standard costing process.
  • Work with Suppliers. Storage sites and Finance to schedule and perform periodic inventory reviews and audits.
  • Support design and implementation on an Enterprise Resource Planning system (ERP) for inventory management related activities.
  • Support design and execution of the recall process.
  • Perform other supply chain related activities and projects as needed.

Requirements:

  • B.S. / B.A. degree.
  • 3 – 6+ years’ experience working in a manufacturing or supply chain setting (pharma or biotech highly preferred).
  • Familiar with Inventory Mgmt & Supply Chain processes.
  • Microsoft Excel Experience.
  • Database experience preferred.
  • Detail Oriented.
  • Very Organized.
  • Strong Analytic Skills.
  • Problem Solving Mindset and Skills.
  • Good communication skills.
  • ERP experience preferred.
  • All Vaxcyte employees require vaccination against COVID-19.
Reports to: Executive Director, Global Supply Chain
Location: San Carlos, CA
Compensation:
The compensation package will be competitive and includes comprehensive benefits and an equity component.
Salary Range: $130,000 – $156,000
Send resumes to:
Vaxcyte, Inc.
825 Industrial Road, Suite 300
San Carlos, CA 94070
We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.