Medical Director, North America

Rhythm Pharmaceuticals

Rhythm Pharmaceuticals

Boston, MA, USA
Posted on Friday, June 7, 2024
Company Overview
Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients and their families living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases and provide meaningful support for healthcare providers and patients and their families. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to adapt, learn, and our tenacity to overcome barriers, together.

Opportunity Overview
As Medical Director in North America Medical Affairs, you will be a strategic thought partner providing expert medical leadership and contribute to the development and execution of the launch strategy as part of the Medical Affairs strategy, lead content development, KOL education programs, and support our cross-functional field teams for North America. As a key member of the North America Medical team, reporting to the Senior Medical Director, North America, you will be accountable for advancing Rhythm’s scientific leadership in Rare Neuroendocrine Diseases including hypothalamic Obesity and other pipeline indications. You will thrive in this role if you are a self-starter and a highly collaborative individual who cares to have impact on patients in rare disease space.

Responsibilities and Duties
  • Contribute to and execute a highly efficient, integrated medical strategy for Rare Obesity in the North America region, with a priority focus on hypothalamic Obesity along with pipeline.
  • Develop and maintain KOL engagement with key stakeholders to bring relevant insights in the launch of potential future indications
  • Work in close collaboration with Field Medical, Global Medical Affairs, Commercial, Customer Engagement, and other cross-functional partners to ensure engagement strategy, positioning and scientific educational initiatives are consistently aligned with Rhythm’s strategy and KOL knowledge needs.
  • Collaborate with experts and medical organizations to develop and implement clinical practice guidelines, and diagnostic algorithms.
  • Generate medical insights across different areas to inform cross-functional strategies and tactics
  • Collaborate with cross-functional field teams to identify gaps and provide North America strategic input for the development of disease state and product specific educational and messaging opportunities in internal and external-facing materials and initiatives.
  • Lead medical content development, and other high impact strategic activities such as advisory boards, medical education with help of external vendor management to ensure timely delivery of medical materials and initiatives.
  • Work closely with functional groups as subject matter medical expert, including field medical, area development managers, commercial and patient advocacy.
  • Foster strong relationships with internal and external stakeholders to identify unique opportunities to improve and evolve educational and training content.
  • Manage budget for assigned projects.
Qualifications and Skills
  • Advanced degree, MD, PharmD or Ph.D. required; fellowship or other additional post doctorate experience highly preferred
  • 8-10 years of pharmaceutical industry experience, with relevant HQ-based Medical Affairs or related experience
  • Substantial understanding and experience in rare disease is required
  • Prior launch experience required
  • Excellent written and communication skills, highly organized and able to manage supporting multiple initiatives
  • A curious learner who is focused on patient outcomes and values collaboration and advancing scientific understanding
  • Team player willing to roll up sleeves and bring expertise to other departments as needed
This role is based out of our corporate office in Boston, Massachusetts. Rhythm operates in a hybrid-work model. Candidates applying must be willing and able to be in the Boston office in coordination with their department and business needs. This role may involve 30% travel.

More About Rhythm
Our lead asset, IMCIVREE® (setmelanotide), is a precision medicine designed to treat hyperphagia, an insatiable, pathological hunger characterized by abnormal food-seeking behaviors, and early- or rapid-onset severe obesity caused by an impairment of a pathway in the hypothalamus called the melanocortin-4 receptor (MC4R) pathway. IMCIVREE® is the first and only approved therapy for certain rare MC4R pathway diseases in the United States, Europe, Great Britain and several other countries. In collaboration with leading experts
across the world, Rhythm is advancing the most comprehensive clinical research program ever initiated in MC4R pathway diseases, including a Phase 3 trial for acquired hypothalamic obesity. In addition, we are leveraging our extensive genetic database, global network of researchers, a track record of regulatory successes and global commercial infrastructure to develop a full portfolio of treatment options to patients struggling with hyperphagia and severe obesity and ensuring they get the treatment that is right for them.


We continue to advance care and precision medicines that address rare diseases. We are focused on expanding access to IMCIVREE® to reach more patients and developing novel therapies for other rare neuroendocrine diseases, including congenital hyperinsulinism. Rhythm’s headquarters is in Boston, MA.