Protein Process Development Scientist

Quantum SI

Quantum SI

San Diego, CA, USA
Posted on Thursday, May 25, 2023

Company Description

Quantum-Si is pioneering a new generation of technology to create the market of Next Generation Protein Sequencing (NGPS). Similar to Next Generation DNA Sequencing (NGS), which gave us a blueprint of what could happen by studying our DNA, NGPS enables an unbiased view of the proteome through improved scale, resolution, and sensitivity leading to better understanding of disease and improved general health.

We operate at the intersection of biochemistry, chemistry, hardware, molecular biology, photonics, semiconductor chips, and software with a goal to drive a digital transformation of a $44 billion dollar proteomics market.

Join us on the journey to transform healthcare, motivated by the idea that the products you work on will change the lives of millions of people around the world.

Job Description

We seek a highly skilled and motivated Protein Process Development Scientist to join our dynamic team. As a Protein Process Development Scientist, you will be vital in developing and optimizing protein purification and manufacturing processes. Your expertise and innovative thinking will contribute to advancing our company's protein sequencing products.

As part of our team, your core responsibilities will be:

  • Develop and optimize protein purification processes: Design, execute, and troubleshoot protein purification processes to achieve high product yield, purity, and quality. Evaluate and implement novel purification strategies and technologies.
  • Process optimization and scale-up: Conduct optimization studies to enhance protein manufacturing processes' efficiency, scalability, and robustness. Collaborate with cross-functional teams to transfer operations from laboratory to pilot and production scales.
  • Characterization and analysis: Perform analytical and biochemical characterization of proteins using techniques such as SDS-PAGE, HPLC, mass spectrometry, and spectroscopy. Generate and analyze data to understand protein behavior and optimize process conditions.
  • Technology evaluation: Stay updated on the latest advancements in protein purification technologies and industry best practices. Evaluate and introduce new technologies, equipment, and methodologies to improve process efficiency and productivity.
  • Documentation and reporting: Maintain accurate and detailed records of experimental procedures, results, and observations. Prepare technical reports, protocols, and standard operating procedures (SOPs) to document process development activities.
  • Collaboration and communication: Work with multidisciplinary teams, including Research and Development, Quality Control, and Manufacturing, to align process development objectives and timelines. Effectively communicate progress, challenges, and recommendations to key stakeholders.
  • Compliance and safety: Adhere to applicable regulatory guidelines and quality standards in all process development activities. Maintain a safe and organized laboratory environment and actively participate in safety initiatives.


Baseline skills/experiences/attributes:

  • D. or Master's degree in Biochemistry, Biotechnology, Chemical Engineering, or a related field with a strong focus on protein purification and process development.
  • 5-7 years of industry experience in protein purification process development, optimization, and scale-up.
  • Proficiency in various protein purification techniques, chromatography, and filtration methods.
  • Hands-on experience with protein characterization techniques and analytical tools.
  • Strong analytical and problem-solving skills with keen attention to detail.
  • Ability to work independently and in a team-oriented environment.
  • Excellent communication and presentation skills to effectively collaborate with cross-functional teams and convey technical information to both technical and non-technical audiences.
  • Knowledge of regulatory requirements and quality management systems in the biopharmaceutical industry is a plus.

You Deeply Identify with Core Quantum-Si Values:

  • Team: We are stronger as a unit and collectively committed to the goal and each other.
  • Accountability: Be accountable to the goal, the team and yourself.
  • Passion: We are enthusiastic and dedicated to expanding scientific understanding and its impact.
  • Excellence: Be aggressive and have a sense of urgency but take pride in each task taken on.
  • Transparency: We align as an organization and communicate success and challenge.
  • Competitive: We do not fear but learn from making mistakes. We play to win!
  • Diversity: Each individual regardless of role makes a difference and impacts our progress.

Additional Information

We offer great perks:

  • Competitive salaried compensation - we value our employees and show it
  • Equity - we want every employee to be a stakeholder
  • Fully covered medical insurance plan along with a generous company sponsored health reimbursement account, and dental & vision coverage - as a health-tech company, we place great worth on our teams’ well-being
  • Company paid life insurance, short term and long term disability
  • Flexible Paid Time Off - personal responsibility for managing our own time, workload and results plus 14 paid holidays inclusive of MLK Day, Juneteenth, Indigenous People’s Day and Veterans Day
  • Parental Leave - we provide a generous 10 week parental leave and additional 6-8 weeks pregnancy related leave for birthing parents
  • Pre-tax commuter benefits - we make your commute more reasonable
  • Free onsite meals
  • 401k plan - we facilitate your retirement goals
  • Beautiful office in the heart of San Diego
  • The opportunity to build a revolutionary healthcare product and save millions of lives!

The estimated base salary range for this role based in the United States of America is: $ - $. Compensation decisions are dependent on several factors including, but not limited to, level of the position, an individual’s skills, knowledge and abilities, location where the role is to be performed, internal equity, and alignment with market data. Additionally, all full-time employees are eligible for our discretionary bonus program and equity as part of the compensation package.

For this role, we provide visa assistance for qualified candidates.

Quantum-Si does not accept agency resumes.

Quantum-Si is an E-Verify and equal opportunity employer regardless of race, color, ancestry, religion, gender, national origin, sexual orientation, age, citizenship, marital status, disability or Veteran status. All your information will be kept confidential according to EEO guidelines.