Career Opportunities in the Foresite Capital Network

We are seeking a creative medicinal chemist to join our parallel synthesis group at Nurix.

• This candidate will be responsible for the synthesis of chemical libraries (small molecules, bifunctional degraders) using a variety of automated parallel synthesis strategies.
• The candidate will interact with Medicinal Chemists to optimize and validate chemical routes for transfer to parallel synthesis platforms.
• This candidate will participate in the design, development, optimization, and validation of automation configurations for high-throughput parallel synthesis applications.

Key Responsibilities:

• Synthesis of chemical arrays using automated synthesis platforms.
• Design of hypothesis driven SAR chemical arrays.
• Development of new scripts for automation robots, such as liquid handler, parallel synthesizer, and high throughput analytical systems.
• Development of new methodologies for solid phase and /or solution parallel automated synthesis approaches.
• Maintaining automation systems and development of new protocols.
• Contribution to scientific strategies and goals within a project team setting.
• Maintaining proper experimental documentation, reporting during team / department meetings.

Desired Skills and Experience

Requirements:
- Doctorate degree and 2-5 years of medicinal chemistry or pharmaceutical research experience

OR

Master's / Bachelor degree and 5-10 years of medicinal chemistry or pharmaceutical research experience

To be successful in this position the candidate will have:

• A demonstrated knowledge of high throughput parallel synthesis techniques with application to medicinal chemistry problematics.
• A proven laboratory work experience with high throughput analytical and compound purification systems.
• A proven experience with cheminformatics tools, structures enumeration applications, ELNs.
• Strong organization, time management, problem-solving skills ,and pro-active attitude.
• Excellent communication, and leadership skills.
• Maintain a very productive lab presence.
• Prior experience with operating and programming liquid handling robotics platforms (Preferred, not mandatory).
• Knowledge of solid phase chemistry principles and/or polymer-bound catalysts/reagent used in solution phase chemistry (Preferred, not mandatory).

Fit with Nurix Culture and Values

• Strong team orientation and highly collaborative
• Solutions and results-oriented focus
• Hands-on approach; resourceful and open to diverse points of view

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