Research Associate, Cloning

LifeMine Therapeutics

LifeMine Therapeutics

Cambridge, MA, USA
Posted on Thursday, August 24, 2023

Job Summary

LifeMine Therapeutics is seeking an Operations Leader, with extensive expertise in advanced molecular cloning and biochemical techniques in an industry setting. Knowledge and experience of bacterial and yeast molecular biology and microbiology, as well as laboratory automation is a requirement. This role will assist efforts to engineer and manipulate genetic systems for production of novel molecules and support LifeMine’s drug discovery platform.

Job Responsibilities

  • Lead operations for a small team dedicated to plasmid design and construction
  • Supervise assembly and confirmation of DNA constructs for fungal strain engineering
  • Develop new capabilities and technologies to help increase throughput
  • Collect rigorous quality control metrics and develop standard operating procedures
  • Actively communicate results with the broader strain engineering group and design new experiments for process optimization

Job Requirements

  • B.S. with >5 years or M.S. with >3 years of industry experience in molecular biology, biochemistry, microbiology or related field
  • Experience with a variety of advanced DNA cloning and assembly approaches, including Gibson, Golden Gate and yeast recombination
  • Experience with E. coli and yeast microbiology and genetics for cloning
  • Experience with laboratory information management systems (LIMS), high throughput techniques and/or lab automation
  • Excellent written and oral communication skills
  • Strong organizational skills and ability to multi-task during daily routine
  • A sense of adventure and excitement to build a new company and work in a highly dynamic multidisciplinary team environment