Director, IT Infrastructure and Operations

Kiniksa Pharmaceuticals

Kiniksa Pharmaceuticals

IT, Other Engineering, Operations
Lexington, MA, USA
Posted on Saturday, May 11, 2024

Reporting to the Vice President of IT and serving as a member of the IT Leadership team, the Director - IT Infrastructure and Operations will be responsible for leading an organization tasked with the delivery of reliable, secure, and efficient IT services and technology capabilities to the organization. The role requires a combination of technology leadership on IT infrastructure, operations and security technologies, disciplined process execution and performance management, and great communication skills.

This role is based in our Lexington office. Our office-based employees follow a hybrid schedule of 4 days in the office, and 1 day remote.

Responsibilities (including, but not limited to):

  • Lead a hybrid team of employees and external vendors in managing and administering the IT infrastructure, collaboration, communications, and security toolsets
  • Manage day to day operations of the IT infrastructure company-wide, including but not limited to planning and management of computer operations; systems and database administration; user administration and support; change/release management in scope; DR/business continuity; network operations; telecom and cloud services
  • Manage and drive improvement of the full suite of data and device security, and endpoint control solutions
  • Manage O365, e-mail and other collaboration tools, ensure secure and resilient protection of company data
  • Maintain GxP systems in a validated/qualified state; execute qualification and Computer Systems Validation activities and documentation as needed
  • Maintain IT Operations and Security SOPs consistent with our Quality Management program, including controls, monitoring, and recovery procedures
  • Play a leadership role in the company’s cyber security program, assessing risk, defining mitigation plans, and leading day-to-day Cyber Security monitoring and incident response activities
  • Maintain a technology roadmap, identifying opportunities to introduce new technology or maximize the use of existing technologies where appropriate and aligned to business needs
  • Develop the skills and competencies and manage performance of the IT Operations team
  • Actively communicate and problem solve within IT and across the organization


  • 15+ years’ experience as an information technology leader with a hands on technical foundation
  • Bachelor’s degree in Computer Science, Information Management, or related field (MBA or advanced relevant technical degree strongly desired), required
  • A minimum of 7 years managing a team of direct reports is required
  • International experience is highly desired
  • Understanding of the business processes and GxP compliance requirements (Predicate Rule, Part 11, Computer Systems Validation, Data Integrity) in a biotech or pharmaceutical environment is highly desired. Working knowledge of applicable US and European data privacy laws
  • Experience with most or all of the following:
    1. AWS or MS Azure cloud services
    2. Microsoft O365
    3. Okta or other cloud based IDP
    4. Next Generation Firewalls (Palo Alto, Fortigate, Cisco Firepower, or similar)
    5. Network architecture concepts, including VLANs, 802.1x, S2S VPNs, etc.
    6. VMWare
    7. Enterprise storage and backup solutions
    8. Microsoft Desktop O/S and enterprise administration tools (eg: Intune/Autopilot)
    9. Endpoint Protection tool suites
    10. Email Filtering and security platforms
    11. Active Directory and Azure Authentication
    12. Vulnerability scanning tools
    13. SIEM log aggregation/management/monitoring tools/solutions
  • Experience leading a cyber-security program. Prior experience remediating a major event a plus
  • Experience defining and executing projects with business stakeholders
  • Proven record of success in leading infrastructure operations that are scalable, cost-effective, and blended with outsourced resources
  • Proven record of acting as a thought leader and subject matter expert on infrastructure and security, collaborating with applications technical owners and cross functional business groups
  • Results oriented and the ability work independently and meet deadlines
  • Ability to work in a fast-paced small company environment, remaining flexible while being cost conscious
  • Strong interpersonal skills and the ability to develop and maintain effective relationships in a diverse organization
  • Proven ability to build and lead a lean, high-performance team
  • Demonstrate highest ethical standards
  • Strong commitment to compliance and ethical standards
  • Proficient with Microsoft Office suite (i.e., Word, PowerPoint, Excel, Outlook, SharePoint, etc.)
  • Salary is commensurate with experience
  • Kiniksa Benefits Summary - USA

Kiniksa is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, transgender status, age, genetics, national origin, protected veteran status, or disability status, or any other legally protected category. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.