Senior Staff Bioinformatics Scientist, Translational Bioinformatics (Menlo Park CA) #3497



Menlo Park, CA, USA
Posted on Wednesday, February 14, 2024
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.
We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.
GRAIL is headquartered in Menlo Park, California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.
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GRAIL is seeking a highly motivated and experienced Senior Staff Scientist to join our Translational Bioinformatics team working within GRAIL’s Research division. You will play a key role in cancer detection, disease and treatment response monitoring as well as in characterizing disease biology, with the ultimate goal of improving patient outcomes across the continuum of cancer treatment. You will work with diverse teams including research, clinical, software, operations, product development, and external collaborators to develop new diagnostic products for oncology drug discovery and translational research. You’ll report to the Senior Director of Translational Bioinformatics team.
GRAIL is headquartered in Menlo Park California. This position enjoys a hybrid environment in which employees will be onsite 2 days a week.


  • Lead team projects and conduct bioinformatics analyses to solve complex scientific problems with significant functional impact
  • Define strategic direction and analysis plans to drive innovative research projects internally or externally and/or improve products, infrastructure, or processes
  • Provide technical leadership to a technical area or a product development workstream
  • Collaborate across teams and disciplines to solve problems and act as a trusted cross-functional partner
  • Lead and contribute to scientific publications, conference presentations, technical reports, and internal knowledge sharing activities to disseminate research findings and promote scientific excellence within the organization
  • Mentor junior members of the team

Preferred Qualifications

  • Ph.D. with 8+ years experience in bioinformatics, computational biology, or a related field, including at least 2+ years industry experience, with background in oncology and experience in drug discovery and/or translational research
  • Strong technical skills, proficient in R or Python programming, solid understanding of statistical modeling and machine learning techniques (regression, classification, clustering, survival analysis, longitudinal modeling)
  • Expert knowledge in the analysis and interpretation of at least one of the following data types: genomic, epigenomic, transcriptomic, or proteomic data
  • Clear, positive, and proactive communicator in verbal and written communications
  • Demonstrated experience in managing complex biomedical projects with internal and external dependencies
  • Mastery of working collaboratively under tight deadlines and balancing the needs of multiple key stakeholders
  • Results-oriented: superb follow-through, drive, and creative problem-solving
The estimated, full-time, annual base pay scale for this position is $200,000 - $230,000. Actual base pay will consider skills, experience, and location.
Based on the role, colleagues may be eligible to participate in an annual bonus plan tied to company and individual performance, or an incentive plan. We also offer a long-term incentive plan to align company and colleague success over time.
In addition, GRAIL offers a progressive benefit package, including flexible time-off, a 401k with a company match, and alongside our medical, dental, vision plans, carefully selected mindfulness offerings.
GRAIL is an Equal Employment Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. We will reasonably accommodate all individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. GRAIL maintains a drug-free workplace.