Senior Director, Supply Chain

Editas Medicine

Editas Medicine

Sales & Business Development, Operations
Cambridge, MA, USA
Posted on Thursday, April 11, 2024

At Editas, we’re driven by a collective purpose, to bring transformative and life changing therapies to people living with serious diseases with the greatest unmet needs. This fuels our drive to excel in scientific innovation, allowing us to harness the power and potential of CRISPR/Cas9 and CRISPR/Cpf1 (Cas12a) gene editing.

We believe our people are at the core of everything we do, and we’re committed to cultivating a culture where every individual feels valued and included. To do this, we strive to integrate belonging, inclusivity, diversity, and equity into every aspect of our organization.

Together, we are leading the way towards a healthier and more equitable future.

Position Summary

This position will oversee supply chain of late phase and commercial manufacturing production through distribution, manage CMO generated materials/intermediates for both internal and external partners, oversee GMP and non-GMP material management, long range production planning at all current and future production locations, and the utilization and distribution of non-GMP materials at all locations.

Key Responsibilities:

As the Sr. Director, Supply Chain, you will be responsible for:

  • Building out all aspects of the Supply Chain Team for a late-stage autologous cell therapy including: The supply and raw material planning function, supply network design and optimization strategy, inventory ownership and ensuring a strong supply and raw materials plan handoff to internal and external partners
  • This role will report to the VP of Supply Chain and Technical Operations and partner with leadership in TechOps, ClinOps, Finance, CMC and Program Teams to lead short-term integrated production and raw materials planning and long-range strategic supply chain planning of Editas’ product portfolio
  • This role will partner with Clinical Operations to secure clinical supply needs and with Commercial, CMC, Engineering and PD for commercial supply chain design and capabilities of late stage clinical development programs
  • This role will be accountable for designing and implementing core capabilities that drive proactive modeling and decision analysis of supply network and product strategy including governance, S&OP business processes and technology to support this work
  • The role will be responsible for developing and executing an inventory management program including design and policy to ensure raw and critical material availability
  • Develop and implement supply chain analytics, planning, and resilience processes and policy across the global supply chain for all stages of the product lifecycle
  • Oversee and manage global end to end supply planning and network design as Editas transitions from clinical to commercial stage company
  • Oversee and manage S&OP process
  • Collaborate cross-functionally with ClinOps and Program teams to ensure accurate demand forecasts and scenarios/analytics
  • Responsible for supply network analysis to support tactical and strategic decision making
  • Coordinate with Finance, Program Teams, CMC and PD to ensure robust modeling of product and network scenarios to support decision-making in governance forums
  • Communicate demand uncertainties or risks and develop options for optimizing supply network capacity and capabilities
  • Ensure optimal economics, and adequate supply chain security in partnership with Finance for Budget, LRP and capital planning processes
  • Direct activities of all functions involved in planning, warehousing, logistics to ensure control of materials from the receipt of raw materials to the delivery of the finished product including inventory controls
  • Oversee and publish metrics to reflect the effectiveness and efficiency of department activities including supply chain KPIs on inventory, responsiveness and costs
  • Implement KPIs that drives accountability and improvement in both operational and financial metrics
  • Participate in the design & implementation of SAP Phase 3 and IT roadmap in preparation for commercial launch
  • Design and execute shipping validation studies