Senior Manufacturing Associate - 2333

Editas Medicine

Editas Medicine

Waltham, MA, USA
Posted on Friday, October 21, 2022

What if you could repair broken genes? That is the question we ask ourselves at Editas Medicine. We’re focused on translating the power and potential of the CRISPR/Cas9 and CRISPR/Cpf1 (also known as Cas12a) genome editing systems into a robust pipeline of medicines for people living with serious diseases around the world. Our goal is to discover, develop, manufacture, and commercialize trans-formative, durable, precision genomic medicines for many diseases.

We’re looking for talented, dedicated, passionate people to join our team and help us pioneer this field and do big, bold things that have never been achieved before.

Are you full of hope, possibilities, and a belief that, working together, we can truly revolutionize the development of medicines to help patients around the world. If the answer is yes, then Editas Medicine is the place for you.

Key Responsibilities & Accountabilities:

  • Lead/Train a clinical MFG team in a clean room environment while fully gowned following GMP guidelines and using aseptic technique.
  • Generate, revise, review and approve SOPs, batch records and other quality documents to support internal manufacturing projects and ensure all documents are maintained to accurately reflect the most current process
  • Lead troubleshooting of process and equipment problems with manufacturing, process development and quality teams
  • Operate instrumentation required for cell manufacturing and gene editing.
  • Perform duties as dictated by standard operating procedures (SOPs) for cellular product manufacturing and under GxP guidelines as directed.
  • Work in a Biological Safety Cabinet for open processing operations.
  • Accurately complete batch record documentation, all appropriate equipment log entries, and GMP documentation.
  • Maintain orderly lab space.
  • Maintain sufficient inventory of supplies and reagents for performance of duties. Clean and maintain laboratory equipment in good working order.
  • Prepare solutions and culture media as appropriate.
  • Work in compliance with all appropriate laboratory regulatory and safety requirements

Knowledge, Skills & Capabilities:

  • Must have experience with Cell Therapies
  • Must have experience working in a GMP environment
  • Must have technical knowledge to work as a liaison between MFG and Process Development
  • Self-motivated and detailed-oriented. Willing to be trained to new techniques
  • Ability to read and understand Standard Operating Procedures
  • Preferred experience with gene editing processes
  • Preferred experience with GMP document creation/revision
  • Preferred experience with Quality Management Systems
  • Strong organizational skills and attention to detail with the ability to multi-task, problem-solve, prioritize assignments, and adjust priorities to meet goals in a fast-paced environment
  • Good communication skills and the ability to work independently, and as part of a team
  • Preferred experience with Excel and Microsoft Office applications

Education & Relevant Work Experience:

  • Bachelor’s degree with 2-4 years of relevant experience
  • High School diploma and 4+ or more years related industry experience or an Associate's Degree in Life Sciences/Engineering field with 3+ year of GMP Manufacturing experience will be considered
  • Ability to pass sterile gowning qualification required


  • Previous cleanroom or cGMP experience is highly desirable
  • Fill/finish or aseptic technique training strongly preferred

Shift Differential Pay:

Editas Medicine offers Premium Pay in the form of a 10% shift differential added to the hourly rates of employees who are regularly scheduled to work second shift, which is defined as a work shift falling between the hours of 2:00 – 10:00 PM (local time). This differential will be removed for employees who move to a shift that occurs during regular business hours.

Physical & Travel Requirements:

  • Must be willing and able to travel between Cambridge and Waltham locations

Benefits Summary:

Editas provides a comprehensive array of benefits to all employees, including a Blue Cross Blue Shield PPO Medical Plan, a company-funded Health Savings Account, Dental and Vision Insurance, Life and Disability Insurance, Dependent Care Account, Tuition Reimbursement, 401(k) plan with company match, Employee Stock Purchase Plan, Employee Assistance Plan, Wellness Programs, and a flexible Paid Time Off policy.