Senior Software Engineer



Software Engineering
Prague, Czechia
Posted on Monday, May 27, 2024

Company Description

DNAnexus is a leading provider of secure, scalable, and intuitive biomedical data analysis software and bioinformatics applications for the life sciences and healthcare communities. The company actively manages and supports more than 80 petabytes of complex genomic, multi-omic, and clinical datasets on behalf of a growing network of collaborations with large-scale biobanks, as well as leading pharmaceutical, clinical diagnostic, academic research, and government organizations. Over 40,000 scientists across 48 countries are now using the highly collaborative, cloud-based, end-to-end platform to gain data-driven insights that can advance scientific discovery, accelerate precision medicine, and improve patient care.

Job Description

Who We’re Looking For

You are a software engineer who wants to design and build core technologies for scaling up systems to thousands of servers for managing and analyzing petabytes of data. At the same time, you have a special passion for scalability and sustainability of software development. In this position, you will work on evolving an event-driven automation platform. You will be responsible for designing a product that is highly available, fault tolerant and responsive from the ground up. You will also collaborate with other engineering teams to ensure that our development practices are sustainable, so that our product can stay secure and compliant, and that our engineers can work easily with top-notch technologies. You enjoy learning something new everyday, and you are motivated to aim for the best development practices possible.


  • Build scalable infrastructure specifically targeted to the cloud environment
  • Design, document, and implement new web service APIs for internal and external services
  • Contribute to the continuous evolution of our engineering best practices
  • Implement CI pipelines to automate anything that can be automated in our process
  • Enable integration of DNAnexus services with external systems


  • Few years of core software development experience, strong computer science background
  • Knowledge of JavaScript/Node.js/TypeScript; you will encounter code in other languages (Python, BASH, Lua); although you don’t need to be expert in all, we are looking for someone flexible and willing to learn
  • Team-oriented, with strong communication skills
  • Experience with Docker and general familiarity with the Linux shell
  • Demonstrated ability to pick up new technologies and quickly adapt to new paradigms
  • Understanding of database management systems - relational and NoSQL
  • Eligibility to work in the Czech Republic

Nice to have

  • Knowledge of AWS, including VPC, IAM, Lambda
  • Experience with monorepo management tools like Rush.JS
  • Experience in building and maintaining scalable distributed systems
  • Experience with MongoDB

What We Care About

  • Curiosity and humility. We are dedicated to learning and constantly improving. We hope you also value "unknown unknowns" and have a natural drive to figure out how everything works.
  • Agility and ownership. Our teams have a high degree of freedom on how they build their systems, but they also take full ownership of what they deliver, in the long run.
  • Proactivity. An internal drive to leave things in a better state than they are. Going above and beyond to help our codebase to stay healthy.
  • Monitoring and automation. We strongly believe that a fully automated system is key to rapid iterations, while an extensive set of metrics highlights what needs to be done.
  • Balancing research and product. We value staying up-to-date on cutting edge research, while also shipping meaningful products enabling researchers to fulfill their mission.

Additional Information

Headquartered in Mountain View, California, with over 220 team members across the United States and Europe, DNAnexus is experiencing rapid growth and market adoption. With the support of leading investors including Google Ventures and Blackstone, and trusted by hundreds of the world's biomedical leaders, the company is at the innovative forefront with our precision health data cloud to drive scientific breakthroughs. If you are interested in joining our team, please apply today!

DNAnexus will provide the necessary support to enable the ideal candidate to work remotely within the Czech Republic.